CNTFR Antibody

Datasheet
Code CSB-PA005684GA01HU
Product Type Purified Rabbit Anti human PolyClonal Antibody
Size US$685
Uniprot No. P26992
Immunogen Human CNTFR
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Tested Applications ELISA,WB
Storage Buffer PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method Antigen Affinity Purified
Isotype IgG
Alias ciliary neurotrophic factor receptor;CNTFR;MGC1774 ;
Immunogen Species Homo sapiens (Human)
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Target Names CNTFR
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Details This gene encodes a hematopoeitin/interferon-class receptor belonging to the cytokine superfamily of receptors. The encoded gene product represents the CNTF-specific alpha subunit of a heterotrimer forming the CNTF receptor complex, which also includes LIFR and gp130. The receptor is attached to the membrane by a glycosyl-phosphatidylinositol linkage and contains an immunoglobulin-like C2-type domain and a fibronectin type-III domain. Signal transduction requires that CNTF bind first to this alpha component, which permits the recruitment of gp130 and LIFR beta to form the tripartite receptor complex. Signal transduction stimulates gene expression, cell survival or differentiation in a variety of neuronal cell types. Alternative splicing has been observed at this locus and two variants, both encoding the same protein, have been identified.
HGNC 2170
RGD 1303100
MGI 99605
Still Have Questions? Leave a Message or Start an on-line Chat
Function Binds to CNTF. The alpha subunit provides the receptor specificity.
Subcellular Location Cell membrane, Lipid-anchor, GPI-anchor
Protein Families Type I cytokine receptor family, Type 3 subfamily
Tissue Specificity Nervous system and skeletal muscle.
Database Links

HGNC: 2170

OMIM: 118946

KEGG: hsa:1271

STRING: 9606.ENSP00000242338

UniGene: Hs.129966

Pathway Jak-STAT signaling pathway

Related Products

CNTFR Antibodies

CNTFR Antibodies for Homo sapiens (Human)

CNTFR Antibodies for

CNTFR Antibodies for Human

CNTFR Proteins

CNTFR Proteins for Homo sapiens (Human)

Most popular with customers

Newsletters

Get all the latest information on Events, Sales and Offers. Sign up for newsletter today.

Copyright © 2007-2018 www.cusabio.com CUSABIO TECHNOLOGY LLC All Rights Reserved.

Wait!

Join the 25,000 subscribers to get research hotpots, technical tips, latest information on events, sales and offers.

Sign up now!

We don't deal in spam.