COL6A3 Antibody

Datasheet
Code CSB-PA053506
Product Type Polyclonal Antibody
Size US$297
Uniprot No. P12111
Image
  • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using Collagen VI α3 antibody.
  • Immunofluorescence analysis of HeLa cells, using Collagen VI α3 antibody.
Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
Immunogen Synthesized peptide derived from internal of Human Collagen VI α3.
Raised in Rabbit
Species Reactivity Human,Mouse
Specificity The antibody detects endogenous levels of total Collagen VI α3 protein.
Tested Applications ELISA,IHC,IF;IHC:1:50-1:100,IF:1:100-1:500
Relevance Collagen VI acts as a cell-binding protein.

Chu M.-L., EMBO J. 9:385-393(1990).
Zanussi S., J. Biol. Chem. 267:24082-24089(1992).
Liu T., J. Proteome Res. 4:2070-2080(2005).
Form Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality Polyclonal
Alias Collagen alpha-3(VI) chain; CO6A3;
Immunogen Species Homo sapiens (Human)
Target Names COL6A3
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Collagen VI acts as a cell-binding protein.
Involvement in disease Bethlem myopathy 1 (BTHLM1); Ullrich congenital muscular dystrophy 1 (UCMD1); Dystonia 27 (DYT27)
Subcellular Location Secreted, extracellular space, extracellular matrix
Protein Families Type VI collagen family
Database Links

HGNC: 2213

OMIM: 120250

KEGG: hsa:1293

STRING: 9606.ENSP00000295550

UniGene: Hs.233240

Pathway PI3K-Akt signaling pathway
Focal adhesion

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