COL6A3

The COL6A3 gene encodes for the alpha-3 chain of type VI collagen, a protein essential for the extracellular matrix structure. Known as alpha-3 procollagen, it is also referred to as COL6A3. This protein plays a crucial role in collagen chain trimerization and integrin pathway, contributing to cell adhesion and matrix assembly. COL6A3 mutations are associated with Bethlem myopathy and Ullrich congenital muscular dystrophy, which are characterized by muscle weakness and degeneration. In terms of drug development, research is ongoing to identify COL6A3 inhibitors for therapeutic intervention in these diseases.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

COL6A3 Antibody (CSB-PA053506)

Validated Data

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using Collagen VI α3 antibody.

Immunofluorescence analysis of HeLa cells, using Collagen VI α3 antibody.

Human Collagen alpha-3(VI) chain (COL6A3) ELISA kit (CSB-EL005753HU)

Validated Data

Code: CSB-EL005753HU

Size: 96T,5×96T,10×96T

Sensitivity: 0.39 ng/mL

Detection Range: 1.56 ng/mL-100 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following COL6A3 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

COL6A3 Antibodies

COL6A3 Proteins

COL6A3 ELISA Kits

COL6A3 Antibodies

COL6A3 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA053506	COL6A3 Antibody	Human,Mouse	ELISA,IHC,IF
CSB-PA007093	COL6A3 Antibody	Human,Mouse	IHC, IF, ELISA

COL6A3 Proteins

COL6A3 Proteins for Gallus gallus (Chicken)

Code	Product Name	Source
CSB-YP005753CH CSB-EP005753CH CSB-BP005753CH CSB-MP005753CH CSB-EP005753CH-B	Recombinant Chicken Collagen alpha-3 (VI) chain (COL6A3), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

COL6A3 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP005753HU1 CSB-EP005753HU1 CSB-BP005753HU1 CSB-MP005753HU1 CSB-EP005753HU1-B	Recombinant Human Collagen alpha-3 (VI) chain (COL6A3), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF005753HUa6	Recombinant Human Collagen alpha-3 (VI) chain (COL6A3), partial	in vitro E.coli expression system
CSB-CF005753HU	Recombinant Human Collagen alpha-3 (VI) chain (COL6A3), partial	in vitro E.coli expression system

COL6A3 ELISA Kit

COL6A3 ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-EL005753HU	Human Collagen alpha-3(VI) chain (COL6A3) ELISA kit	serum, plasma, tissue homogenates	0.39 ng/mL

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COL6A3

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