CSF2RA Antibody

Datasheet
Code CSB-PA006046LA01HU
See More Details
Size US$299
Uniprot No. P15509
Image
  • Immunofluorescence staining of HepG2 cells with CSB-PA006046LA01HU at 1:466, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA006046LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA006046LA01HU at dilution of 1:100

Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
Immunogen Recombinant Human Granulocyte-macrophage colony-stimulating factor receptor subunit alpha protein (23-320AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:200-1:500
Relevance Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells.
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Granulocyte-macrophage colony-stimulating factor receptor subunit alpha (GM-CSF-R-alpha) (GMCSFR-alpha) (GMR-alpha) (CDw116) (CD antigen CD116), CSF2RA, CSF2R CSF2RY
Immunogen Species Human
Research Area Immunology
Target Names CSF2RA
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells.
Involvement in disease Pulmonary surfactant metabolism dysfunction 4 (SMDP4)
Subcellular Location Cell membrane, Single-pass type I membrane protein, SUBCELLULAR LOCATION: Isoform 3: Secreted, SUBCELLULAR LOCATION: Isoform 4: Secreted, SUBCELLULAR LOCATION: Isoform 6: Secreted
Protein Families Type I cytokine receptor family, Type 5 subfamily
Database Links

HGNC: 2435

OMIM: 300770

KEGG: hsa:1438

UniGene: Hs.520937

Pathway Jak-STAT signaling pathway
Hematopoietic cell lineage

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