CSF2RA Antibody

Datasheet
Code CSB-PA046967
Product Type Polyclonal Antibody
Former Code(s) CSB-PA444679
Size US$297
Uniprot No. P15509
Image
  • Western blot analysis of extracts from COLO205 cells, using CSF2RA antibody.
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunogen Synthesized peptide derived from Internal of Human CSF2RA.
Raised in Rabbit
Species Reactivity Human
Specificity The antibody detects endogenous levels of total CSF2RA protein.
Tested Applications ELISA,WB;WB:1:500-1:3000
Relevance Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells.

Gearing D.P., EMBO J. 8:3667-3676(1989).
Nakagawa Y., J. Biol. Chem. 269:10905-10912(1994).
Crosier K.E., Proc. Natl. Acad. Sci. U.S.A. 88:7744-7748(1991).

Form Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality Polyclonal
Alias Granulocyte-macrophage colony-stimulating factor receptor subunit alpha; GM-CSF-R-alpha; GMCSFR-alpha; GMR-alpha; CDw116
Immunogen Species Homo sapiens (Human)
Target Names CSF2RA
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells.
Involvement in disease Pulmonary surfactant metabolism dysfunction 4 (SMDP4)
Subcellular Location Cell membrane, Single-pass type I membrane protein, SUBCELLULAR LOCATION: Isoform 3: Secreted, SUBCELLULAR LOCATION: Isoform 4: Secreted, SUBCELLULAR LOCATION: Isoform 6: Secreted
Protein Families Type I cytokine receptor family, Type 5 subfamily
Database Links

HGNC: 2435

OMIM: 300770

KEGG: hsa:1438

UniGene: Hs.520937

Pathway Jak-STAT signaling pathway
Hematopoietic cell lineage

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