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| Code | CSB-PA006949LC01HU |
| Size | US$299 |
| Uniprot No. | Q9NR61 |
| Immunogen | Recombinant Human Delta-like protein 4 protein (44-345AA) |
| Raised in | Rabbit |
| Species Reactivity | Human |
| Tested Applications | ELISA |
| Relevance | Involved in the Notch signaling pathway as Notch ligand (PubMed:11134954). Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting (PubMed:20616313). Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types (By similarity). During spinal cord neurogenesis, inhibits V2a interneuron fate (PubMed:17728344). |
| Form | Liquid |
| Conjugate | FITC |
| Storage Buffer | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method | >95%, Protein G purified |
| Isotype | IgG |
| Clonality | Polyclonal |
| Alias | Delta-like protein 4 (Drosophila Delta homolog 4) (Delta4), DLL4 |
| Immunogen Species | Human |
| Protocols | ELISA Protocol |
| Research Area | Neuroscience |
| Target Names | DLL4 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
| Function | Involved in the Notch signaling pathway as Notch ligand |
| Involvement in disease | Adams-Oliver syndrome 6 (AOS6) |
| Subcellular Location | Cell membrane, Single-pass type I membrane protein |
| Tissue Specificity | Expressed in vascular endothelium. |
| Database Links |
HGNC: 2910 OMIM: 605185 KEGG: hsa:54567 STRING: 9606.ENSP00000249749 UniGene: Hs.511076 |
| Pathway |
Notch signaling pathway
Th1 and Th2 cell differentiation |
DLL4 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA073786 | DLL4 Antibody | Human,Mouse | ELISA,IHC |
| CSB-PA831848 | DLL4 Antibody | Human,Mouse | ELISA,IHC |
DLL4 Antibodies for Human
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA006949LA01HU | DLL4 Antibody | Human | ELISA, WB, IF |
| CSB-PA006949LB01HU | DLL4 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA006949LD01HU | DLL4 Antibody, Biotin conjugated | Human | ELISA |
DLL4 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP878862HU CSB-EP878862HU CSB-BP878862HU CSB-MP878862HU |
Recombinant Human Delta-like protein 4(DLL4),partial | Yeast E.coli Baculovirus Mammalian cell |
DLL4 ELISA Kit for Homo sapiens (Human)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-EL006949HU | Human Delta-like protein 4(DLL4) ELISA kit | serum, plasma, tissue homogenates | 5.8 pg/mL |
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Species Reactivity: Human
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