Code | CSB-PA007825HA01HU |
Size | US$166 |
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The ESM1 Antibody (Product code: CSB-PA007825HA01HU) is Non-conjugated. For ESM1 Antibody with conjugates, please check the following table.
Application | Recommended Dilution |
---|---|
IHC | 1:20-1:200 |
The ESM1 polyclonal antibody is raised in the rabbit against a recombinant protein mapping within 20-184 amino acids of human EMS1 protein. This ESM1 antibody is available as the unconjugated IgG isoform. It only reacts with human EMS1 protein. The purity of the ESM1 polyclonal antibody is over 95% using protein G purified. Its specificity for human EMS1 protein has been verified with ELISA and IHC applications.
Its target protein ESM1 mainly promotes angiogenesis by binding to integrin αvβ3, thus stimulating endothelial cell proliferation and migration, which are necessary for the formation of new blood vessels. In addition to its role in angiogenesis, ESM1 also plays a role in inflammation. It is induced by pro-inflammatory cytokines such as TNF-α and IL-1β and is involved in the regulation of leukocyte recruitment and adhesion to endothelial cells. ESMI protein is frequently overexpressed in many cancer types.
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