GRPEL1 Antibody

Datasheet

Code	CSB-PA875707ESR1HU
Size	US$166
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Image	Western blot All lanes: GRPEL1 antibody at 2.65µg/ml Lane 1: A431 whole cell lysate Lane 2: 293T whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 24 kDa Observed band size: 24, 26 kDa Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA875707ESR1HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA875707ESR1HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) GRPEL1 Polyclonal antibody

Uniprot No.

Q9HAV7

Target Names

GRPEL1

Alternative Names

FLJ25609 antibody; GREPEL 1 antibody; GREPEL1 antibody; GrpE like 1 antibody; GrpE like 1 mitochondrial antibody; GrpE like protein cochaperone antibody; GrpE protein homolog 1 mitochondrial antibody; GrpE protein homolog 1; mitochondrial antibody; GRPE1_HUMAN antibody; GRPEL 1 antibody; Grpel1 antibody; HMGE antibody; Mt GrpE#1 antibody; Mt-GrpE#1 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human GrpE protein homolog 1, mitochondrial protein (1-217AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins.

Gene References into Functions

Data suggest that two putative NEF (nucleotide exchange factors) orthologs, GRPEL1 and GRPEL2, modulate function of mitochondrial HSP70 (mtHSP70); both GRPEL1 and GRPEL2 associate with mtHSP70 as hetero-oligomeric subcomplex and regulate mtHSP70 transport. (GRPEL = mitochondrial GrpE-like protein; HSP70 = heat-shock protein 70) PMID: 28848044
The low resolution structure of human GrpE presented suggests that GrpE is a symmetric dimer when not bound to DnaK PMID: 12840016

Subcellular Location

Mitochondrion matrix.

Protein Families

GrpE family

Database Links

HGNC: 19696

OMIM: 606173

KEGG: hsa:80273

STRING: 9606.ENSP00000264954

UniGene: Hs.443723

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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