IL3RA Antibody

Datasheet
Code CSB-PA925610
Size US$299
Uniprot No. P26951
Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA925610(IL3RA Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • Gel: 8%SDS-PAGE,Lysate: 40 μg,,Primary antibody: CSB-PA925610(IL3RA Antibody) at dilution 1/200 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 30 seconds
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunogen Synthetic peptide of Human IL3RA
Raised in Rabbit
Species Reactivity Human,Mouse
Tested Applications ELISA,WB,IHC;ELISA:1:2000-1:5000,WB:1:500-1:2000,IHC:1:25-1:100
Relevance The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3.
Form Liquid
Conjugate Non-conjugated
Storage Buffer -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method Antigen affinity purification
Isotype IgG
Alias interleukin 3 receptor, alpha (low affinity)
Immunogen Species Homo sapiens (Human)
Target Names IL3RA
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function This is a receptor for interleukin-3.
Subcellular Location Membrane, Single-pass type I membrane protein
Protein Families Type I cytokine receptor family, Type 5 subfamily
Database Links

HGNC: 6012

OMIM: 308385

KEGG: hsa:3563

STRING: 9606.ENSP00000327890

UniGene: Hs.632790

Pathway Jak-STAT signaling pathway
PI3K-Akt signaling pathway
Apoptosis
Hematopoietic cell lineage

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