ITCH Antibody

Code CSB-PA060278
Size US$167

Product Details

Uniprot No. Q96J02
Target Names ITCH
Alternative Names ITCH; E3 ubiquitin-protein ligase Itchy homolog; Itch; Atrophin-1-interacting protein 4; AIP4; NFE2-associated polypeptide 1; NAPP1
Raised in Rabbit
Species Reactivity Human,Mouse
Immunogen Synthesized peptide derived from Human AIP4 around the non-phosphorylation site of Y420.
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Isotype IgG
Purification Method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form Liquid
Tested Applications WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:40000
Protocols Western Blotting(WB) Protocol
ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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Target Data

Function Acts as an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates
Involvement in disease Autoimmune disease, multisystem, with facial dysmorphism (ADMFD)
Subcellular Location Cell membrane, Peripheral membrane protein, Cytoplasmic side, Cytoplasm, Nucleus, Early endosome membrane, Peripheral membrane protein, Cytoplasmic side, Endosome membrane, Peripheral membrane protein, Cytoplasmic side
Tissue Specificity Widely expressed.
Database Links

HGNC: 13890

OMIM: 606409

KEGG: hsa:83737

STRING: 9606.ENSP00000363998

UniGene: Hs.632272

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