MIB1 Antibody

1. M1B-1 antigen was shown to increase the risk. High birth weight, pesticide exposure (childhood exposure, and parental occupational exposure) and maternal consumption of cured meat during pregnancy may also increase the risk of onset of childhood brain tumours PMID: 27212451
2. In the absence of PCM1, Mib1 destabilizes Talpid3 through poly-ubiquitylation and suppresses cilium assembly. PMID: 27146717
3. The aim of the study was to evaluate the caspase-3 and survivin expression in correlation with MIB-1 expression in gliomas of various grade. PMID: 26995334
4. provided evidences that miR-10 regulates human endothelial cells behaviour through targeting Mib1 as well PMID: 26825552
5. these results identify the interaction between Mib1 and Plk4 as a new and important element in the control of centriole homeostasis. PMID: 25795303
6. Expression of MIB1 ligase protein, human was correlated with tumor grade and Figo stages. PMID: 26204652
7. Data show how E3 ubiquitin protein ligase Mind bomb protein recognizes notch receptor ligands. PMID: 25747658
8. a significant survival benefit for p16-positive vaginal cancers compared with p16-negative cancers for stages I and II. No difference was observed in survival for MIB-1-positive tumors PMID: 25319982
9. Invasive adenomas have a higher inducible nitric oxide synthase, and this correlated with the MIB-1 PMID: 24008756
10. This is the first published study ever assessing the expression of COX-2, p16 and Ki67 markers in ductal carcinoma in situ breast tumors. PMID: 25077370
11. Data show that the E3 ubiquitin ligase, mind bomb 1 (Mib1), interacts with and ubiquitinates SMN and facilitates its degradation. PMID: 23615451
12. MIB-1 was found to be associated with estrogen receptors in the stromal component PMID: 23442362
13. implicate NOTCH signaling in left ventricular noncompaction and indicate that MIB1 mutations arrest chamber myocardium development, preventing trabecular maturation and compaction PMID: 23314057
14. MIB1 negatively regulates TNFalpha- and IL1beta-induced NF-kappaB target gene activation PMID: 22184009
15. RYK interacts both physically and functionally with the E3 ubiquitin MIB1. MIB1 is sufficient to activate Wnt/CTNNB1 signaling and this activity depends on endogenous RYK. PMID: 21875946
16. Data demonstrate that c-mip interacts with Dip1 and upregulates DAPK, which blocks the nuclear translocation of ERK1/2. PMID: 20018188
17. Neuralized-2 regulates a Notch ligand in cooperation with Mind bomb-1 PMID: 17003037
18. DAPK is found in two distinct immune complexes, one containing HSP90 and CHIP and a second complex containing only DIP1/Mib; strict modulation of DAPK activities by HSP90 heterocomplexes is critical for regulation of apoptosis and cellular homeostasis PMID: 17324930
19. Comparative genomic hybridization and immunohistochemical assessment of EGFR, PTEN, p53, and MIB-1 expression in 13 oligodendrogliomas, one oligoastrocytoma and 23 high-grade astrocytomas is reported. PMID: 17390041
20. The interaction between Mib1 and cFLIP decreases the association of caspase-8 with cFLIP, which activates caspase-8 and induces cell death PMID: 19710364

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HGNC: 21086

OMIM: 608677

KEGG: hsa:57534

STRING: 9606.ENSP00000261537

UniGene: Hs.140903