MPL Antibody

Datasheet
Code CSB-PA005848
Size US$167
Uniprot No. P40238
Image
  • Western Blot analysis of MCF7 cells using CD110 Polyclonal Antibody.
Protocols Western Blotting(WB) Protocol
ELISA Protocol
Immunogen Synthesized peptide derived from the Internal region of Human CD110.
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Tested Applications WB,ELISA;WB:1/500-1/2000.ELISA:1/20000
Form Liquid
Conjugate Non-conjugated
Storage Buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Alias MPL; TPOR; Thrombopoietin receptor; TPO-R; Myeloproliferative leukemia protein; Proto-oncogene c-Mpl; CD110
Immunogen Species Homo sapiens (Human)
Target Names MPL
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Receptor for thrombopoietin. May represent a regulatory molecule specific for TPO-R-dependent immune responses.
Involvement in disease Congenital amegakaryocytic thrombocytopenia (CAMT); Thrombocythemia 2 (THCYT2); Myelofibrosis with myeloid metaplasia (MMM)
Subcellular Location Cell membrane, Single-pass type I membrane protein, Golgi apparatus, Cell surface
Protein Families Type I cytokine receptor family, Type 1 subfamily
Tissue Specificity Expressed at a low level in a large number of cells of hematopoietic origin. Isoform 1 and isoform 2 are always found to be coexpressed.
Database Links

HGNC: 7217

OMIM: 159530

KEGG: hsa:4352

STRING: 9606.ENSP00000361548

UniGene: Hs.82906

Pathway Jak-STAT signaling pathway

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