MYL12B Antibody

Code CSB-PA015308GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
Alternative Names
ML12B_HUMAN antibody; MLC 2A antibody; MLC-2 antibody; MLC-2a antibody; MLC-B antibody; MLC20 antibody; MRLC2 antibody; MYL12B antibody; MYLC2B antibody; Myosin light chain 12B regulatory antibody; Myosin regulatory light chain 12B antibody; myosin regulatory light chain 2 antibody; Myosin regulatory light chain 2-B antibody; myosin regulatory light chain 2-B; smooth muscle isoform antibody; Myosin regulatory light chain 20 kDa antibody; Myosin regulatory light chain MRLC2 antibody; myosin; light chain 12B; regulatory antibody; OTTHUMP00000162244 antibody; OTTHUMP00000165806 antibody; OTTHUMP00000165807 antibody; OTTHUMP00000165808 antibody; SHUJUN-1 antibody; smooth muscle isoform antibody
Raised in
Species Reactivity
Human MYL12B
Immunogen Species
Homo sapiens (Human)
Purification Method
Antigen Affinity Purified
It differs from different batches. Please contact us to confirm it.
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
Troubleshooting and FAQs
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Phosphorylation triggers actin polymerization in vascular smooth muscle. Implicated in cytokinesis, receptor capping, and cell locomotion.
Gene References into Functions
  1. phosphorylated MRLC temporally controls its own accumulation, but not that of actin, in cultured mammalian cells. PMID: 22374324
  2. The study data show that manipulation of the activation sites (Thr18/Ser19) significantly alters myosin II function in a number of these assays while manipulation of the putative inhibitory sites (Ser1/Ser2/Thr9) does not. PMID: 22136066
  3. These results suggest that 2P-MRLC has a role different from that of 1P-MRLC at the midzone, and is not a subunit of myosin II. PMID: 22166199
  4. These results suggest that EGCG inhibits the cell growth by reducing the MRLC phosphorylation and this effect is mediated by the 67LR. PMID: 15946647
Tissue Specificity
Ubiquitously expressed in various hematopoietic cells.
Database Links

HGNC: 29827

KEGG: hsa:103910

STRING: 9606.ENSP00000237500

UniGene: Hs.190086

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