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| Code | CSB-PA945056 |
| Size | US$297 |
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| Have Questions? | Leave a Message or Start an on-line Chat |
| Full Product Name | Rabbit anti-Rattus norvegicus (Rat) Mapt Polyclonal antibody | ||||
| Uniprot No. | P19332 | ||||
| Target Names | Mapt | ||||
| Alternative Names |
Mapt antibody; Mtapt antibody; Tau antibody; Microtubule-associated protein tau antibody; Neurofibrillary tangle protein antibody; Paired helical filament-tau antibody; PHF-tau antibody
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| Raised in | Rabbit | ||||
| Species Reactivity | Human,Mouse,Rat | ||||
| Immunogen | Peptide sequence around aa. 725-729(T-G-S-I-D) derived from Rat Tau | ||||
| Immunogen Species | Rattus norvegicus (Rat) | ||||
| Clonality | Polyclonal | ||||
| Purification Method | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide | ||||
| Concentration | It differs from different batches. Please contact us to confirm it. | ||||
| Form | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | ||||
| Tested Applications | ELISA,WB | ||||
| Recommended Dilution |
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| Protocols | ELISA Protocol Western Blotting(WB) Protocol |
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| Troubleshooting and FAQs | Antibody FAQs | ||||
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | ||||
| Lead Time | Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time. |
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| Function |
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
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| Subcellular Location | Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell projection, axon. Cell projection, dendrite. Secreted. |
| Tissue Specificity | Expressed in neurons. The larger forms (isoform tau-A and isoform tau-B) are preferentially expressed in the peripheral nervous system while the other are expressed in the central nervous system. Low amounts of the larger forms are also found in limited a |
| Database Links |
STRING: 10116.ENSRNOP00000006856 UniGene: Rn.2455 |
