PAG 1 Antibody, HRP conjugated

Code CSB-PA644917LB01BO
Size US$299
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Product Details

Uniprot No. Q29432
Alternative Names Pregnancy-associated glycoprotein 1 antibody; PAG 1 antibody; EC 3.4.23.- antibody; Pregnancy-specific protein B antibody; PSP-B antibody
Raised in Rabbit
Species Reactivity Bovine
Immunogen Recombinant Bovine Pregnancy-associated glycoprotein 1 protein (54-380AA)
Immunogen Species Bos taurus (Bovine)
Conjugate HRP
Clonality Polyclonal
Isotype IgG
Purification Method >95%, Protein G purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
(From Uniprot)
Appears to be proteolytically inactive.
Gene References into Functions
  1. This study examines expression patterns of the genes SERPINA14, PAG, and PAG2 at the fetal-maternal interface in dairy heifers experimentally infected with N caninum during the second trimester of pregnancy, when most abortions takes place in natural conditions. PMID: 27045629
  2. The clinical implications of these findings are that following infection with N. caninum, most cows will experience some level of placental damage and that this injury correlates with foetal fluid PAG levels and pH. PMID: 26936628
  3. These findings indicate that IFN-gamma production correlates negatively and the production of antibodies against N. caninum is uncorrelated with plasma pregnancy-associated glycoproteins levels. PMID: 24456132
  4. Restraint stress for 2 h during early pregnancy in heifers increased blood cortisol, but it did not affect the concentrations of progesterone and PAG-1 between days 30 to 40 of gestation. PMID: 21872319
Subcellular Location Secreted, extracellular space
Protein Families Peptidase A1 family
Tissue Specificity Trophoblast and placental tissue. Produced specifically in the invasive binucleate cells of the placenta. Becomes detectable in maternal serum soon after implantation.
Database Links

KEGG: bta:281964

STRING: 9913.ENSBTAP00000025593

UniGene: Bt.15401

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