PLA2G4D Antibody

Datasheet

Code	CSB-PA008908
Size	US$100
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Product Details
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Target Background

Product Details

Uniprot No.

Q86XP0

Target Names

PLA2G4D

Alternative Names

cPLA2 delta antibody; cPLA2-delta antibody; cPLA2delta antibody; Cytosolic phospholipase A2 delta antibody; PA24D_HUMAN antibody; Phospholipase A2 group IVD antibody; phospholipase A2; group IVD (cytosolic) antibody; Pla2g4d antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Synthesized peptide derived from the Internal region of Human cPLA2-δ.

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Form

Liquid

Tested Applications

IHC, ELISA

Recommended Dilution

Application	Recommended Dilution
IHC	1:100-1:300
ELISA	1:40000

Protocols

Immunohistochemistry (IHC) Protocol
ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function

Calcium-dependent phospholipase A2 that selectively hydrolyzes glycerophospholipids in the sn-2 position. Has a preference for linoleic acid at the sn-2 position.

Gene References into Functions

These findings suggested that the polymorphism of PLA2G4D rs4924618 may have a protective influence on the SPTB susceptibility in a Chinese population, supporting a role for genetics in the association between PG synthesis and preterm birth. PMID: 28440406
The findings suggest that PLA2 inhibition or CD1a blockade may have therapeutic potential for psoriasis. PMID: 27670592
study defined eight additional recurrently mutated genes in SMZL; these genes are CREBBP, CBFA2T3, AMOTL1, FAT4, FBXO11, PLA2G4D, TRRAP and USH2A. PMID: 24349473
Observational study of gene-disease association. (HuGE Navigator) PMID: 19913121
Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) PMID: 20628086
cPLA(2)delta exhibits a unique distribution pattern compared with that of known cPLA(2) subtypes and may play a critical role in inflammation in psoriatic lesions PMID: 14709560
Observational study of gene-disease association. (HuGE Navigator) PMID: 18686860
Observational study of gene-disease association. (HuGE Navigator) PMID: 16213696

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Subcellular Location

Cytoplasm, cytosol. Membrane; Peripheral membrane protein; Cytoplasmic side.

Tissue Specificity

Expressed in stratified squamous epithelia, such as those in skin and cervix, but not in other tissues. Strongly expressed in the upper spinous layer of the psoriatic epidermis, expressed weakly and discontinuously in atopic dermatitis and mycosis fungoid

Database Links

HGNC: 30038

OMIM: 612864

KEGG: hsa:283748

STRING: 9606.ENSP00000290472

UniGene: Hs.380225

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

MAPK signaling pathway VEGF signaling pathway Vascular smooth muscle contraction Necroptosis Ras signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Oxidative Phosphorylation Phospholipase D signaling pathway Glutamatergic synapse

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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