PPP2R3B Antibody

Code CSB-PA896533ESR2HU
Size US$167Purchase it in Cusabio online store
(only available for customers from the US)
Image
  • Western blot
    All lanes: PPP2R3B antibody at 2.1µg/ml + HL60 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 66, 21 kDa
    Observed band size: 66 kDa

  • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA896533ESR2HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA896533ESR2HU at dilution of 1:100

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Product Details

Description

The PPP2R3B polyclonal antibody (CSB-PA896533ESR2HU) is produced in rabbits immunized with the recombinant human PPP2R3B protein (356-575AA). It occurs as an unconjugated IgG. It underwent antigen affinity purification and reached a relatively high purity. And it only reacts with human PPP2R3B protein, a protein phosphatase 2A regulatory subunit that interacts with the origin of replication component, CDC6, and has been linked to regulation of autophagy. This PPP2R3B antibody has been quality tested in ELISA, WB, and IHC applications.

Full Product Name Rabbit anti-Homo sapiens (Human) PPP2R3B Polyclonal antibody
Uniprot No. Q9Y5P8
Target Names PPP2R3B
Alternative Names NY REN 8 antibody; NY REN 8 antigen antibody; P2R3B_HUMAN antibody; PP2A B'' subunit PR48 antibody; PP2A subunit B isoform PR48 antibody; PP2A subunit B PR48 isoform antibody; PPP2R3B antibody; PPP2R3L antibody; PPP2R3LY antibody; PR 48 antibody; PR48 antibody; Protein phosphatase 2 (formerly 2A) regulatory subunit B'' beta antibody; Protein phosphatase 2 regulatory subunit B'' beta antibody; Protein phosphatase 2A 48 kDa regulatory subunit antibody; Serine/threonine protein phosphatase 2A 48kDa regulatory subunit B antibody; Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta antibody
Raised in Rabbit
Species Reactivity Human
Immunogen Recombinant Human Serine/threonine-protein phosphatase 2A regulatory subunit B\\\'\\\' subunit beta protein (356-575AA)
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Antigen Affinity Purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form Liquid
Tested Applications ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Data

Function The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
Gene References into Functions
  1. PPP2R3B codes for the PR70 protein, a regulatory substrate-recognizing subunit of protein phosphatase 2A. PR70 decreased melanoma growth by negatively interfering with DNA replication and cell cycle progression through its role in stabilizing CDC6-chromatin licensing and CDT1 interaction PMID: 27974665
  2. Results show the crystal structure of PR48/PR70, at 2.0 A degrees resolution with two domain elongated structure and two Ca2+ binding EF-hands Scattering data. PMID: 25007185
Subcellular Location Nucleus
Database Links

HGNC: 13417

OMIM: 300339

KEGG: hsa:28227

STRING: 9606.ENSP00000375080

UniGene: Hs.124942

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