SRP54 Antibody

Code CSB-PA022675GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
SRP54
Alternative Names
Signal recognition particle 54 kDa protein antibody; Signal recognition particle 54kDa antibody; SRP 54 antibody; SRP54 antibody; SRP54_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human SRP54
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Plays a role in proliferation and differentiation of granulocytic cells, neutrophils migration capacity and exocrine pancreas development.
Gene References into Functions
  1. autosomal dominant mutations in SRP54, a key member of the cotranslation protein-targeting pathway, lead to syndromic neutropenia with a Shwachman-Diamond-like phenotype. PMID: 28972538
Subcellular Location
Nucleus speckle. Cytoplasm. Endoplasmic reticulum.
Protein Families
GTP-binding SRP family, SRP54 subfamily
Database Links

HGNC: 11301

OMIM: 604857

KEGG: hsa:6729

STRING: 9606.ENSP00000216774

UniGene: Hs.167535

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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