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Code | CSB-PA675446LC01HU |
Size | US$299 |
Have Questions? | Leave a Message or Start an on-line Chat |
Full Product Name | Rabbit anti-Homo sapiens (Human) TIGIT Polyclonal antibody |
Uniprot No. | Q495A1 |
Target Names | TIGIT |
Alternative Names |
DKFZp667A205 antibody; ENSMUSG00000071552 antibody; FLJ39873 antibody; RGD1563191 antibody; T cell immunoreceptor with Ig and ITIM domains antibody; TIGIT antibody; TIGIT_HUMAN antibody; V-set and immunoglobulin domain containing 9 antibody; V-set and immunoglobulin domain-containing protein 9 antibody; V-set and transmembrane domain containing 3 antibody; V-set and transmembrane domain-containing protein 3 antibody; VSIG9 antibody; VSTM3 antibody; Washington University cell adhesion molecule antibody; WUCAM antibody
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Raised in | Rabbit |
Species Reactivity | Human |
Immunogen | Recombinant Human T-cell immunoreceptor with Ig and ITIM domains protein (22-141AA) |
Immunogen Species | Homo sapiens (Human) |
Conjugate | FITC |
Clonality | Polyclonal |
Isotype | IgG |
Purification Method | >95%, Protein G purified |
Concentration | It differs from different batches. Please contact us to confirm it. |
Buffer | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Form | Liquid |
Troubleshooting and FAQs | Antibody FAQs |
Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Lead Time | Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time. |
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Function |
Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.
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Gene References into Functions |
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Subcellular Location | Cell membrane; Single-pass type I membrane protein. |
Tissue Specificity | Expressed at low levels on peripheral memory and regulatory CD4+ T-cells and NK cells and is up-regulated following activation of these cells (at protein level). |
Database Links |
HGNC: 26838 OMIM: 612859 KEGG: hsa:201633 STRING: 9606.ENSP00000373167 UniGene: Hs.421750 |