TNFSF12 Antibody

Datasheet

Code	CSB-PA023987ESR1HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human prostate tissue using CSB-PA023987ESR1HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human epityphlon tissue using CSB-PA023987ESR1HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) TNFSF12 Polyclonal antibody

Uniprot No.

O43508

Target Names

TNFSF12

Alternative Names

APO 3 ligand antibody; APO 3L antibody; APO3 ligand antibody; APO3/DR3 ligand antibody; APO3L antibody; DR3LG antibody; MGC129581 antibody; MGC20669 antibody; secreted form antibody; TNF-related weak inducer of apoptosis antibody; TNF12_HUMAN antibody; TNFSF 12 antibody; Tnfsf12 antibody; TNFSF12 protein antibody; Tumor necrosis factor (ligand) superfamily member 12 antibody; Tumor necrosis factor ligand superfamily member 12 antibody; Tumor necrosis factor superfamily member 12 antibody; TWEAK antibody; UNQ181/PRO207 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Tumor necrosis factor ligand superfamily member 12 protein (42-123AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function

Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion.

Gene References into Functions

Observational study of gene-disease association. (HuGE Navigator) PMID: 19913121
Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) PMID: 20628086

Subcellular Location

Cell membrane; Single-pass type II membrane protein.; [Tumor necrosis factor ligand superfamily member 12, secreted form]: Secreted.; [Isoform TWE-PRIL]: Cell membrane; Single-pass membrane protein.

Protein Families

Tumor necrosis factor family

Tissue Specificity

Highly expressed in adult heart, pancreas, skeletal muscle, brain, colon, small intestine, lung, ovary, prostate, spleen, lymph node, appendix and peripheral blood lymphocytes. Low expression in kidney, testis, liver, placenta, thymus and bone marrow. Als

Database Links

HGNC: 11927

OMIM: 602695

KEGG: hsa:407977

UniGene: Hs.54673

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

An Overview of Cell Death: Necrosis and Apoptosis Tumor Necrosis Factor Receptor Superfamily and Apoptosis Does TNF Superfamily Inhibit Cancer or Promote Its Development? Tumor Necrosis Factor (TNF) Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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