TNFSF12 Antibody

Datasheet

Code	CSB-PA004351
Size	US$100
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Image	Western Blot analysis of 293 cells using TWEAK Polyclonal Antibody Western Blot analysis of 293T AD293 HELA HepG2 KB cells using TWEAK Polyclonal Antibody
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Product Details
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Target Background

Product Details

Uniprot No.

O43508

Target Names

TNFSF12

Alternative Names

APO 3 ligand antibody; APO 3L antibody; APO3 ligand antibody; APO3/DR3 ligand antibody; APO3L antibody; DR3LG antibody; MGC129581 antibody; MGC20669 antibody; secreted form antibody; TNF-related weak inducer of apoptosis antibody; TNF12_HUMAN antibody; TNFSF 12 antibody; Tnfsf12 antibody; TNFSF12 protein antibody; Tumor necrosis factor (ligand) superfamily member 12 antibody; Tumor necrosis factor ligand superfamily member 12 antibody; Tumor necrosis factor superfamily member 12 antibody; TWEAK antibody; UNQ181/PRO207 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse

Immunogen

Synthesized peptide derived from the Internal region of Human TWEAK.

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Form

Liquid

Tested Applications

WB, IHC, IF, ELISA

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000
IHC	1:100-1:300
IF	1:200-1:1000
ELISA	1:20000

Protocols

Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function

Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion.

Gene References into Functions

Observational study of gene-disease association. (HuGE Navigator) PMID: 19913121
Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) PMID: 20628086

Subcellular Location

Cell membrane; Single-pass type II membrane protein.; [Tumor necrosis factor ligand superfamily member 12, secreted form]: Secreted.; [Isoform TWE-PRIL]: Cell membrane; Single-pass membrane protein.

Protein Families

Tumor necrosis factor family

Tissue Specificity

Highly expressed in adult heart, pancreas, skeletal muscle, brain, colon, small intestine, lung, ovary, prostate, spleen, lymph node, appendix and peripheral blood lymphocytes. Low expression in kidney, testis, liver, placenta, thymus and bone marrow. Als

Database Links

HGNC: 11927

OMIM: 602695

KEGG: hsa:407977

UniGene: Hs.54673

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

An Overview of Cell Death: Necrosis and Apoptosis Tumor Necrosis Factor Receptor Superfamily and Apoptosis Does TNF Superfamily Inhibit Cancer or Promote Its Development? Tumor Necrosis Factor (TNF) Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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