UGGT2 Antibody

Datasheet

Code	CSB-PA025566GA01HU
Size	$600
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q9NYU1

Target Names

UGGT2

Alternative Names

UGGT2 antibody; UGCGL2 antibody; UGT2UDP-glucose:glycoprotein glucosyltransferase 2 antibody; UGT2 antibody; hUGT2 antibody; EC 2.4.1.- antibody; UDP--Glc:glycoprotein glucosyltransferase 2 antibody; UDP-glucose ceramide glucosyltransferase-like 1 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Human UGCGL2

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation.

Gene References into Functions

In this study, we aimed to clarify the contribution of the noncatalytic domains by comparing activities of truncated forms of recombinant HUGT1/HUGT2 and HUGT1/HUGT2 chimeras with full-length enzymes. PMID: 27496766
The glucosyltransferase activity of UGGT2 has been lacking, leaving it unclear as to whether it has any function in the glycoprotein folding process. PMID: 24415556
HUGT2 cannot activate the catalytic domain of UDP-glucose: glycoprotein glucosyltransferase I PMID: 12913004

Subcellular Location

Endoplasmic reticulum lumen. Endoplasmic reticulum-Golgi intermediate compartment.

Protein Families

Glycosyltransferase 8 family

Tissue Specificity

Higher levels in kidney, pancreas, heart, and skeletal muscle.

Database Links

HGNC: 15664

OMIM: 605898

KEGG: hsa:55757

STRING: 9606.ENSP00000365938

UniGene: Hs.193226

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

The Overview of Organelles Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Protein processing in endoplasmic reticulum Virus Infection

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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