Product Details

Full Product Name

Rabbit anti-Human YWHAH Polyclonal antibody

Uniprot No.

Q04917

Target Names

YWHAH

Alternative Names

14 3 3 protein eta antibody; 14-3-3 eta antibody; 14-3-3 protein eta antibody; 1433F_HUMAN antibody; Brain protein 14-3-3; eta isoform antibody; HGNC:12853 antibody; Protein AS1 antibody; Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein 1 antibody; Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein eta polypeptide antibody; Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein; eta isoform antibody; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein; eta antibody; Tyrosine 3/tryptophan 5 monooxygenase activation protein eta polypeptide antibody; YWHA 1 antibody; YWHA1 antibody; Ywhah antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human 14-3-3 protein eta protein (4-246AA)

Immunogen Species

Human

Conjugate

Biotin

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Related Products

Target Background

Function	Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.
Gene References into Functions	Results show that YWHAZ amplification indicates a better survival trend in bladder cancer. Its knockdown promotes both in vitro and in vivo tumorigenesis in bladder cancer and may be a novel biomarker for bladder cancer. PMID: 29512774 The impact of AKT1 on glucocorticoid receptor (GR)-induced transcriptional activity in cooperation with phospho-serine/threonine-binding protein 14-3-3, was examined. PMID: 27717743 14-3-3 eta isoform colocalizes TDP-43 on the coarse granules in the anterior horn cells of patients with sporadic amyotrophic lateral sclerosis. PMID: 27256400 Extracellular 14-3-3eta activates key signalling cascades and induces factors associated with the pathogenesis of rheumatoid arthritis PMID: 24751211 This study identified YWHAH significantly associated loci with a biologically plausible role in schizophrenia. PMID: 24507884 14-3-3eta may be required for mitotic progression and may be considered as a novel anti-cancer strategy in combination with microtubule inhibitors. PMID: 22562251 This is the first genetic association study of YWHAH with sporadic Creutzfeldt-Jakob disease populations. PMID: 21739144 relocation of p33ING1b from the nucleus to the cytoplasm, where the protein is tethered by 14-3-3eta, participates in tumorigenesis and progression in HNSCC PMID: 21432775 The 14-3-3 eta, beta, gamma and sigma isoforms were negatively expressed in meningioma PMID: 20388496 phosphorylation of 14-3-3 binding site of myeloid leukemia factor 1 by MADM PMID: 12176995 Data demonstrate that 14-3-3 proteins are colocalized with Lewy bodies in Parkinson disease, but there was no specific staining for the 14-3-3 eta subunit. PMID: 12480176 gremlin 1 is overexpressed in human cancers and interacts with YWHAH protein PMID: 16545136 The association of YWHAH with bipolar disorder in a large sample, consisting of 1211 subjects from 318 nuclear families including 554 affected offspring, was investigated. PMID: 19160447 Show More Hide All
Protein Families	14-3-3 family
Tissue Specificity	Expressed mainly in the brain and present in other tissues albeit at lower levels.
Database Links	HGNC: 12853 OMIM: 113508 KEGG: hsa:7533 STRING: 9606.ENSP00000248975 UniGene: Hs.226755

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Check Code：

Code	CSB-PA02174D0Rb
Size	US$299
Image	Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA02174D0Rb at dilution of 1:100
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YWHAH Antibody, Biotin conjugated

Product Details

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Target Background

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