oprF Antibody, HRP conjugated

Code CSB-PA318417LB01EZX
Size US$166
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Product Details

Full Product Name
Rabbit anti-Pseudomonas aeruginosa oprF Polyclonal antibody
Uniprot No.
Target Names
oprF
Alternative Names
oprF antibody; PA1777 antibody; Outer membrane porin F antibody
Raised in
Rabbit
Species Reactivity
Pseudomonas aeruginosa
Immunogen
Recombinant Pseudomonas aeruginosa Outer membrane porin F protein (25-350AA)
Immunogen Species
Pseudomonas aeruginosa
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Has porin activity, forming small water-filled channels. Also has a structural role in determining cell shape and ability to grow in low-osmolarity medium.
Gene References into Functions
  1. OprF (an outer membrane porin, highly conserved in the Pseudomonas) binds human C3b. PMID: 25964476
  2. LecB binds to the outer membrane protein OprF PMID: 23056489
  3. oprF transcription was increased in response to low NaCl or high sucrose concentrations, and this induced transcription was strongly impaired in the absence of SigX. PMID: 22685281
  4. Prevention of disulfide bond formation in OprF increases its pore-forming activity. PMID: 20978537
  5. This is the first study showing a link between OprF, PQS synthesis, T3SS, and virulence factor production PMID: 21189321
  6. Data show that the recombinant plasmid pIRES-tPA-OprF-MyD88 has been successfully constructed and tPA-OprF and MyD88 protein can be highly expressed in transfected cells. PMID: 19257978
  7. findings suggest that OprF could adopt two alternative conformations in the outer membrane and that folding is thermoregulated PMID: 15528532
  8. findings demonstrate that interferon-gamma binds to an outer membrane protein in Pseudomonas aeruginosa, OprF, resulting in the expression of a quorum-sensing dependent virulence determinant, the PA-I lectin PMID: 16051797
  9. analysis of OprF from Pseudomonas aeruginosa PMID: 16397890
  10. OprF exists in two different conformations PMID: 16595653
  11. analysis of Pseudomonas aeruginosa porin OprF PMID: 16617058
  12. Major outer membrane protein F (OprF) is identified as a protein with important functions; mutant Pseudomonas aeruginosa deficient in OprF negates the antibacterial role of host neutrophil elastase both in vitro and in a pneumonia model. PMID: 18802098

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Subcellular Location
Cell outer membrane; Multi-pass membrane protein.
Protein Families
OmpA family
Database Links

KEGG: pae:PA1777

STRING: 208964.PA1777

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