Recombinant Human Pro-epidermal growth factor(EGF) ,partial,Yeast

Code CSB-YP007473HU
Product Type Recombinant Protein
Size Pls inquiry other sizes
Uniprot No. P01133
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer Tris-based buffer,50% glycerol
Species Homo sapiens (Human)
Purity >85% (SDS-PAGE)
Source Yeast
Gene Names EGF
Protein Names Recommended name: Pro-epidermal growth factor Short name= EGF Cleaved into the following chain: 1. Epidermal growth factor Alternative name(s): Urogastrone
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Product Info The following tags are available.
N-terminal His-tagged
Tag-Free
Protein Description Partial
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Function EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. Can induce neurite outgrowth in motoneurons of the pond snail Lymnaea stagnalis in vitro
Involvement in disease Hypomagnesemia 4 (HOMG4)
Subcellular Location Membrane, Single-pass type I membrane protein
Tissue Specificity Expressed in kidney, salivary gland, cerebrum and prostate.
Database Links

HGNC: 3229

OMIM: 131530

KEGG: hsa:1950

STRING: 9606.ENSP00000265171

UniGene: Hs.419815

Pathway ErbB signaling pathway
HIF-1 signaling pathway
Jak-STAT signaling pathway
MAPK signaling pathway
PI3K-Akt signaling pathway
Focal adhesion
Gap junction
Regulation of actin cytoskeleton
Ras signaling pathway
FoxO signaling pathway
Phospholipase D signaling pathway
Rap1 signaling pathway

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