Code | CSB-EP618785HU2 |
Abbreviation | Recombinant Human RIPK1 protein, partial |
MSDS | |
Size | $388 |
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The expression region of this recombinant Human RIPK1 covers amino acids 1-375. The expected molecular weight for the RIPK1 protein is calculated to be 49.4 kDa. The RIPK1 protein was expressed in e.coli. Fusion of the N-terminal 10xHis tag and C-terminal Myc tag into the RIPK1 encoding gene fragment was conducted, allowing for easier detection and purification of the RIPK1 protein in subsequent stages.
Human receptor-interacting Serine/Threonine-Protein kinase 1 (RIPK1) is a pivotal regulator of cell survival and inflammation. Acting as a signaling node in death receptor pathways, RIPK1 controls cell fate decisions by modulating apoptosis, necroptosis, and inflammation. In immunology research, RIPK1 is essential for immune response modulation. Dysregulation of RIPK1 is implicated in inflammatory and autoimmune diseases. In cancer research, its role in cell death pathways makes RIPK1 a potential target for therapeutic intervention. Furthermore, RIPK1 is involved in neurodegenerative disorders. Investigating RIPK1 provides insights into diverse physiological processes, offering avenues for developing treatments targeting cell death, inflammation, and related diseases.There are currently no reviews for this product.