Recombinant Human Transthyretin(TTR)

In Stock
Code CSB-EP025270HU
Product Type Recombinant Protein
Size US$1726Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. P02766
Lead Time 3-7 business days
Relevance Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
Image
  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Storage Buffer Tris-based buffer,50% glycerol
Alias ATTRPrealbumin;TBPA
Species Homo sapiens (Human)
Purity Greater than 90% as determined by SDS-PAGE.
Sequence GPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE
Research Area Transport
Source E.coli
Gene Names TTR
Expression Region 21-147aa
Tag Info N-terminal 6xHis-tagged
Mol. Weight 17.8kDa
Protein Description Full Length of Mature Protein
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
Involvement in disease Amyloidosis, transthyretin-related (AMYL-TTR); Hyperthyroxinemia, dystransthyretinemic (DTTRH); Carpal tunnel syndrome 1 (CTS1)
Subcellular Location Secreted, Cytoplasm
Protein Families Transthyretin family
Tissue Specificity Detected in serum and cerebrospinal fluid (at protein level). Highly expressed in choroid plexus epithelial cells. Detected in retina pigment epithelium and liver.
Database Links

HGNC: 12405

OMIM: 105210

KEGG: hsa:7276

STRING: 9606.ENSP00000237014

UniGene: Hs.427202

Pathway Th17 cell differentiation
Thyroid hormone synthesis

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