Code | CSB-RA296617A0HU |
Size | US$210 |
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Application | Recommended Dilution |
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WB | 1:500-1:5000 |
IHC | 1:50-1:200 |
AIFM1 antibody CSB-RA296617A0HU is a recombinant monoclonal antibody produced from the expression of the plasmids that were constructed by the AIFM1 monoclonal antibody (generated from animals with the human AIFM1 synthesized peptide immunization) DNA sequence in cell lines. This AIFM1 recombinant antibody is a rabbit IgG antibody. It was purified using the affinity-chromatography method. It can recognize and detect the AIFM1 protein from human and rat samples. And it is suitable for ELISA, IHC, and WB analyses.
The target protein AIFM1 is released from the mitochondrial intermembrane space (IMS) during apoptosis and can induce chromatin condensation and DNA fragmentation in a caspase-independent manner. It also functions as a mitochondrial flavin adenine dinucleotide (FAD)-dependent nicotinamide adenine dinucleotide (NADH) oxidoreductase that regulates respiratory complex assembly and function, produces reactive oxygen species (ROS), and coordinates parthanatos.
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