Code | CSB-RA010429A05acHU |
Size | US$210 |
Order now | |
Image |
|
Have Questions? | Leave a Message or Start an on-line Chat |
Application | Recommended Dilution |
---|---|
WB | 1:500-1:2000 |
ICC | 1:50-1:500 |
IF | 1:30-1:200 |
The production of the acetyl-Histone H4 (K5) recombinant monoclonal antibody commences with the cloning of genes encoding the HIST1H4A antibody, which includes both heavy and light chains. These cloned genes are integrated into expression vectors, which are subsequently transfected into host cells. The host cells are cultured for antibody production and secretion. The purified antibody is achieved through affinity chromatography, guaranteeing its purity and efficacy. It is further subjected to comprehensive testing across various applications, including ELISA, WB, ICC, and IF, enabling precise detection of the human HIST1H4A protein acetylated at K5.
Acetylation at H4K5 promotes chromatin decondensation and is primarily associated with transcriptional activation. H4K5 acetylation is involved in DNA repair processes. H4K5 acetylation often occurs in conjunction with other histone modifications, forming a complex regulatory code that fine-tunes gene expression.
There are currently no reviews for this product.