Code | CSB-RA937940A0HU |
Size | US$210 |
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Application | Recommended Dilution |
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FC | 1:50-1:200 |
The CEACAM8 recombinant monoclonal antibody production process is initiated with in vitro cloning, wherein genes for both the heavy and light chains of the CEACAM8 antibody are integrated into expression vectors. These vectors are subsequently introduced into host cells, enabling the recombinant antibody's expression within a cell culture setting. Following expression, the CEACAM8 recombinant monoclonal antibody is meticulously purified from the supernatant of transfected host cell lines using affinity chromatography. Significantly, this antibody exhibits remarkable specificity in its binding to the human CEACAM8 protein and is highly versatile and suitable for ELISA and FC applications.
CEACAM8 is a cell surface receptor primarily found on neutrophils, and its main function is to facilitate the adhesion, migration, and transendothelial passage of neutrophils during the immune response. CEACAM8 is essential for the recruitment of neutrophils to sites of infection or inflammation, where they play a vital role in defending the body against microbial pathogens and contributing to the inflammatory response.
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