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The GPC3 recombinant monoclonal antibody is prepared by cloning the gene fragment encoding human GPC3 protein into the expression vector and subsequently transfecting clones into the cell line for in vitro expression. This GPC3 antibody can detect the endogenous content of the human GPC3 protein. It is purified by the affinity chromatography method. And it has been validated in ELISA, WB, and IF applications.
GPC3 is a cell-surface glycoprotein that exerts important functions in cellular signaling including cell growth, embryogenesis, and differentiation. GPC3 has been associated with hepatocellular carcinoma and a few other cancers.
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