Code | CSB-RA009438MA1MO |
Size | US$210 |
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The Gipr recombinant monoclonal antibody generation typically starts with the insertion of the Gipr antibody-encoding gene into expression vectors. These vectors are subsequently delivered into host cells through polyethyleneimine-mediated transfection methods. The host cells containing these vectors are cultured to produce and release the antibodies. After purification using affinity chromatography, the antibodies undergo testing through ELISA to confirm their recognition of the mouse and rat Gipr proteins. In the functional ELISA, immobilized mouse Gipr protein (CSB-MP009438MO1) at 2 μg/mL can bind this mouse Gipr recombinant monoclonal antibody, with the EC50 of 8.622-11.36 ng/mL.
Gipr is primarily expressed in pancreatic beta cells and adipose tissue, and its activation by GIP has several important functions in the body, particularly in the regulation of glucose metabolism and energy storage.
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