Code | CSB-RA299884A0HU |
Size | US$210 |
Order now | |
Image | |
Have Questions? | Leave a Message or Start an on-line Chat |
Application | Recommended Dilution |
---|---|
WB | 1:500-1:5000 |
HDAC1 serving as the catalytic subunit binds to other proteins such as Sin3, NuRD, and CoREST and then interacts with sequence-specific DNA-binding transcription factors, inhibiting transcription and cooperating with other chromatin modifiers to shape epigenetic programs. HDAC1-involving control of epigenetic modulation is crucial for normal development and tumor progression. Elevated expression of HDAC1 has been found in gastric, prostate, colon, and breast carcinomas. HDAC1 plays a crucial role in the progression of gastric cancer by facilitating the proliferation of cancer cells.
The main steps in the production of this HDAC1 recombinant antibody include immunization; harvest of positive spleen cells; obtaining the antibody sequence by screening and sequencing; expression of the target antibody in mammalian cells; purification. The HDAC1 antibody was produced recombinantly and has many advantages: high reproducibility, specificity and scalability. And has been validated in ELISA, WB.There are currently no reviews for this product.