Code | CSB-RA922556A0HU |
Size | US$210 |
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Application | Recommended Dilution |
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WB | 1:500-1:5000 |
LPAR1, also called Edg2, primarily expressed in the brain, can couple to G protein-coupled receptors (GPCRs) and participate in regulating cell proliferation and survival, migration, cell-cell contact, cytoskeletal alterations, calcium mobilization, adenylyl acylase inhibition, and apoptosis after being stimulated by LPA. LPAR1 deletion causes neurodevelopmental disorders and CNS diseases, such as brain cancer, neuropsychiatric disorders, demyelination diseases, and neuropathic pain. LPAR1 might play a vital role in various benign and malignant diseases by activating the PI3K/AKT pathway.
The production of this recombinant LPAR1 antibody started with immunization. And then the workflow included B cell harvest and enrichment; import single B cell; assays to identify the specificity, affinity & functionality of the cell; export the single B cell; cDNA synthesis and sequencing; express the LPAR1 antibody in mammalian cells. The target LPAR1 antibody was validated in ELISA, WB.There are currently no reviews for this product.