Code | CSB-RA951792A0HU |
Size | US$210 |
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Application | Recommended Dilution |
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WB | 1:500-1:5000 |
The MAPKAPK2 recombinant monoclonal antibody can be used to detect human and mouse MAPKAPK2 proteins in ELISA and WB applications. This antibody is produced using recombinant DNA technology, where the gene coding for the MAPKAPK2 monoclonal antibody is synthesized after sequencing the cDNA of the MAPKAPK2 antibody-producing hybridomas. These hybridomas are generated by fusing myeloma cells and B cells that were isolated from an animal immunized with a synthesized peptide derived from human MAPKAPK2. The synthesized gene is then cloned into a vector and transfected into cells for cultivation. Finally, the resulting MAPKAPK2 recombinant monoclonal antibody is purified through affinity chromatography from the cell culture supernatant.
The MAPKAPK2 protein mainly regulates various cellular processes, including cell growth, differentiation, and apoptosis. MAPKAPK2 is activated by the p38 MAPK pathway, which is a critical regulator of cellular stress response. Once activated, MAPKAPK2 phosphorylates a variety of target proteins, including transcription factors and other kinases, leading to changes in gene expression and cellular activity. Additionally, MAPKAPK2 plays a role in the immune response and has been implicated in a range of diseases, including cancer and neurodegenerative disorders.
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