MAPKAPK2

MAP kinase-activated protein kinase 2 is a protein in humans that is encoded by MAPKAPK2 gene. Stress-activated serine/threonine-protein kinase involved in cytokine production, endocytosis, reorganization of the cytoskeleton, cell migration, cell cycle control, chromatin remodeling, DNA damage response and transcriptional regulation. Following stress, it is phosphorylated and activated by MAP kinase p38-alpha/MAPK14, leading to phosphorylation of substrates. Phosphorylates serine in the peptide sequence, Hyd-X-R-X(2)-S, where Hyd is a large hydrophobic residue. Phosphorylates ALOX5, CDC25B, CDC25C, CEP131, ELAVL1, HNRNPA0, HSP27/HSPB1, KRT18, KRT20, LIMK1, LSP1, PABPC1, PARN, PDE4A, RCSD1, RPS6KA3, TAB3 and TTP/ZFP36. Phosphorylates HSF1.

MAPKAPK2 Antibodies

MAPKAPK2 Antibodies for Homo sapiens (Human)

MAPKAPK2 Proteins

MAPKAPK2 Proteins for Oryctolagus cuniculus (Rabbit)

MAPKAPK2 Proteins for Homo sapiens (Human)

MAPKAPK2 Proteins for Mus musculus (Mouse)

MAPKAPK2 Proteins for Cricetulus longicaudatus (Long-tailed dwarf hamster) (Chinese hamster)

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