Product Details

Uniprot No.

Target Names

Alternative Names

NCR3LG1 antibody; B7H6 antibody; Natural cytotoxicity triggering receptor 3 ligand 1 antibody; B7 homolog 6 antibody; B7-H6 antibody

Species Reactivity

Human

Immunogen

Recombinant Human NCR3LG1 protein

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Monoclonal

Isotype

hIgG1

Clone No.

9E5

Purification Method

Affinity-chromatography

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA

Recommended Dilution

Application	Recommended Dilution
ELISA	1:5000-1:50000

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Description

NCR3LG1, also known as B7-H6, serves as a critical ligand for the natural cytotoxicity triggering receptor 3 (NKp30) expressed on natural killer cells. This interaction plays a fundamental role in NK cell-mediated tumor surveillance, as NCR3LG1 is frequently upregulated on the surface of stressed, infected, or transformed cells while remaining largely absent from healthy tissues. Understanding NCR3LG1 biology has become increasingly important for researchers investigating innate immune responses, tumor immunology, and the development of NK cell-based immunotherapies.

This recombinant monoclonal antibody, clone 9E5, offers researchers the reproducibility and consistency that recombinant technology provides. Because the antibody sequence is defined and produced through recombinant expression rather than traditional hybridoma methods, you can expect reliable performance across experiments and between lot numbers, eliminating a common source of variability in long-term studies.

The antibody has been validated for ELISA applications with human NCR3LG1, demonstrating robust binding activity in functional assays. When immobilized human NCR3LG1 protein was tested, the antibody showed strong interaction with an EC50 in the 10.90–12.22 ng/mL range. Reciprocal binding experiments with immobilized antibody capturing soluble NCR3LG1 yielded even greater sensitivity, with EC50 values of 0.4364–0.5147 ng/mL. These data support the antibody's utility in quantitative detection assays at recommended dilutions ranging from 1:5000 to 1:50000.

Supplied in a glycerol-based PBS buffer for stability, this antibody is well-suited for immunology research programs focused on NK cell biology, tumor immune evasion mechanisms, and checkpoint-related pathways involving the B7 family of immunomodulatory proteins.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Code	CSB-RA737873MA1HU
Size	$49.9
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Image	The Binding Activity of Human NCR3LG1 with Anti-NCR3LG1 Recombinant Antibody Activity: Measured by its binding ability in a functional ELISA. Immobilized Human NCR3LG1(CSB-BP737873HU) at 2 μg/mL can bind Anti-NCR3LG1 recombinant antibody. The EC₅₀ is 10.90-12.22 ng/mL. The Binding Activity of Human NCR3LG1 with Anti-NCR3LG1 Recombinant Antibody Activity: Measured by its binding ability in a functional ELISA. Immobilized Anti-NCR3LG1 recombinant antibody at 2 μg/mL can bind Human NCR3LG1(CSB-MP737873HU-B). The EC₅₀ is 0.4364-0.5147 ng/mL.
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NCR3LG1 Recombinant Monoclonal Antibody

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