The NCR3LG1 gene encodes the Natural cytotoxicity triggering receptor 3 ligand 1 protein, also commonly known as BAT3 - associated protein 1 (BAP1). This protein is crucial in the immune response. It interacts with natural killer cells via the NCR3 receptor, activating these cells to target and eliminate infected or tumor cells. This process is a key part of the innate immune signal pathway.
Dysregulation of NCR3LG1 is associated with certain autoimmune diseases and cancers. In drug development, researchers are exploring ways to modulate its expression or function. Some early - stage research is looking into immunotherapies that could enhance the interaction between NCR3LG1 and NCR3 to improve anti - tumor immunity.
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
Measured by its binding ability in a functional ELISA. Immobilized Anti-NCR3LG1 recombinant antibody(CSB-RA737873MA1HU) at 2 μg/ml can bind Human NCR3LG1. The EC50 is 0.4364-0.5147 ng/mL.
Activity
Measured by its binding ability in a functional ELISA. Immobilized human NCR3(CSB-MP015551HU1) at 5 μg/ml can bind Human NCR3LG1. The EC50 is 111.3-303.1 ng/mL.
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
Measured by its binding ability in a functional ELISA. Immobilized Human NCR3LG1 at 2 μg/ml can bind Anti-NCR3LG1 recombinant antibody(CSB-RA737873MA1HU). The EC50 is 10.90-12.22 ng/mL.
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
NCR3LG1 Recombinant Monoclonal Antibody (CSB-RA737873MA1HU)
Validated Data
The Binding Activity of Human NCR3LG1 with Anti-NCR3LG1 Recombinant Antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human NCR3LG1(CSB-BP737873HU) at 2 μg/mL can bind Anti-NCR3LG1 recombinant antibody. The EC50 is 10.90-12.22 ng/mL.
The Binding Activity of Human NCR3LG1 with Anti-NCR3LG1 Recombinant Antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Anti-NCR3LG1 recombinant antibody at 2 μg/mL can bind Human NCR3LG1(CSB-MP737873HU-B). The EC50 is 0.4364-0.5147 ng/mL.
The following NCR3LG1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
NCR3LG1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA737873LA01HU | NCR3LG1 Antibody | Human | ELISA, WB, IHC, IF |
CSB-PA737873LB01HU | NCR3LG1 Antibody, HRP conjugated | Human | ELISA |
CSB-PA737873LD01HU | NCR3LG1 Antibody, Biotin conjugated | Human | ELISA |
CSB-RA737873MA1HU | NCR3LG1 Recombinant Monoclonal Antibody | Human | ELISA |
NCR3LG1 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-MP737873HU CSB-EP737873HU-B |
Recombinant Human Natural cytotoxicity triggering receptor 3 ligand 1 (NCR3LG1), partial | Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP737873HU | Recombinant Human Natural cytotoxicity triggering receptor 3 ligand 1 (NCR3LG1), partial | E.coli |
CSB-MP737873HU-B | Recombinant Human Natural cytotoxicity triggering receptor 3 ligand 1 (NCR3LG1), partial, Biotinylated (Active) | Mammalian cell |
CSB-YP737873HU | Recombinant Human Natural cytotoxicity triggering receptor 3 ligand 1 (NCR3LG1), partial | Yeast |
CSB-BP737873HU | Recombinant Human Natural cytotoxicity triggering receptor 3 ligand 1 (NCR3LG1), partial (Active) | Baculovirus |