Code | CSB-RA017739A0HU |
Size | US$210 |
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The recombinant monoclonal PDPN antibody is made in vitro using protein technology and DNA recombinant technology. The PDPN antibody was obtained through immunization of an animal with a synthesized peptide derived from human PDPN protein, isolation of B cells, and selection of positive B cells and single clone identification. Sequencing the PDPN antibody and synthesizing the gene. The resulting gene is inserted into a plasmid vector, which is transfected into mammalian cells for expression. The product is the recombinant monoclonal PDPN antibody. It underwent purification using affinity chromatography and is suitable for use in the ELISA to detect the human PDPN protein.
PDPN is a cell-surface mucin-like glycoprotein with pleiotropic functions including regulation of organ development, cell motility, tumorigenesis, and metastasis. Overexpression of PDPN is detected in several tumors and is involved in their malignancy and metastasis. PDPN is widely used as a marker for lymphatic endothelial cells and fibroblastic reticular cells of lymphoid organs and for lymphatics in the skin and tumor microenvironment.
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