Phospho-PXN (Y118) Antibody

Datasheet
Code CSB-RA019112A118phHU
Size US$350
Uniprot No. P49023
Image
  • Western Blot
    Positive WB detected in:Hela whole cell lysate,A549 whole cell lysate,HepG2 whole cell lysate(treated with Calyculin A or EGF)
    All lanes:Phospho-PXN antibody at 1.43μg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 68 KDa
    Observed band size: 68 KDa

Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunogen A synthesized peptide derived from Human Phospho-PXN (Y118)
Species Reactivity Human
Tested Applications ELISA, WB; Recommended dilution: WB:1:500-1:5000
Relevance Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).
Form Liquid
Conjugate Non-conjugated
Storage Buffer Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal
Alias Paxillin, PXN
Immunogen Species Homo sapiens (Human)
Research Area Signal Transduction
Gene Names PXN
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).
Subcellular Location Cytoplasm, cytoskeleton, Cell junction, focal adhesion, Cytoplasm, cell cortex
Protein Families Paxillin family
Database Links

HGNC: 9718

OMIM: 602505

KEGG: hsa:5829

STRING: 9606.ENSP00000228307

UniGene: Hs.446336

Pathway Chemokine signaling pathway
VEGF signaling pathway
Focal adhesion
Regulation of actin cytoskeleton
Leukocyte transendothelial migration

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