Recombinant Cat Follicle-stimulating hormone receptor (FSHR)

Code CSB-CF702060CA
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Source in vitro E.coli expression system
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Product Details

Target Names
FSHR
Uniprot No.
Alternative Names
FSHR; Follicle-stimulating hormone receptor; FSH-R; Follitropin receptor
Species
Felis catus (Cat) (Felis silvestris catus)
Expression Region
18-695
Target Protein Sequence
CHHRICHCWHRVFLCQESKVTEIPSDLPRNAVELRFVLTKLRVIPKGAFSGFGDLEKIEI SQNDVLEVIEANVFFNLSKLHEIRIEKANNLLYIDTDAFQNLPNLRYLLISNTGIKHFPA VHKIQSLQKVLLDIQDNINIHTVERNSFMGLSFESMILWLNKNGIQEIHNCAFNGTQLDE LNLSDNINLEELPNDVFQGASGPVILDISRTRIHSLPSYGLENIKKLRAKSTYNLKKLPS LDKFVALMEASLTYPSHCCAFANWRRPISELHPICNKSILRQEVDDMTQARGQRVSLAED EESSYTKGFDMMYSEFDYDLCNEVVDVTCSPKPDAFNPCEDIMGYDILRVLIWFISILAI TGNIIVLMILITSQYKLTVPRFLMCNLAFADLCIGIYLLLIASVDIYTKSQYHNYAIDWQ TGAGCDAAGFFTVFASELSVYTLTVITLERWHTITHAMQLECKVQLRHAAIIMLLGWIFA FMVALFPIFGISSYMKVSICLPMDIDSPLSQLYVMSLLVLNVLAFVVICCCYAHIYLTVR NPNIVSSSSDTKIAKRMAMLIFTDFLCMAPISFFAISASLKVPLITVSKSKILLVLFYPI NSCANPFLYAIFTKNFRRDFFILLSKFGCYEVQAQTYRSETSSTAHNFHPRNGHCPPAPR VTNSSNYILIPLRHLAKN
Protein Length
Full Length of Mature Protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Function
G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.
Gene References into Functions
  1. No differences in the ovarian expression of FSHR mRNA, LHR protein or mRNA were found between the pre-pubertal and adult cats, but significantly lower FSHR protein expression was found in pre-pubertal cats compared to adult luteal cats. PMID: 28402061
  2. Results describe the expression of follicle stimulating hormone and luteinizing hormone receptors during follicular growth in the domestic cat ovary. PMID: 17219419
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Families
G-protein coupled receptor 1 family, FSH/LSH/TSH subfamily
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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