Recombinant Human Integrin beta-3(ITGB3)

Code CSB-CF011885HU
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P05106
Storage Buffer Tris-based buffer,50% glycerol
Species Homo sapiens (Human)
Sequence GPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT
Source in vitro E.coli expression system
Gene Names ITGB3
Protein Names Recommended name: Integrin beta-3 Alternative name(s): Platelet membrane glycoprotein IIIa Short name= GPIIIa CD_antigen= CD61
Expression Region 27-788
Tag Info N-terminal 10xHis-tagged
Protein Description Full Length of Mature Protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Still Have Questions? Leave a Message or Start an on-line Chat
Function Integrin alpha-V/beta-3 (ITGAV
Involvement in disease Glanzmann thrombasthenia (GT); Bleeding disorder, platelet-type 16 (BDPLT16)
Subcellular Location Cell membrane, Single-pass type I membrane protein, Cell projection, lamellipodium membrane, Cell junction, focal adhesion
Protein Families Integrin beta chain family
Tissue Specificity Isoform beta-3A and isoform beta-3C are widely expressed. Isoform beta-3A is specifically expressed in osteoblast cells; isoform beta-3C is specifically expressed in prostate and testis.
Database Links

HGNC: 6156

OMIM: 173470

KEGG: hsa:3690

STRING: 9606.ENSP00000262017

UniGene: Hs.218040

Pathway PI3K-Akt signaling pathway
Focal adhesion
Regulation of actin cytoskeleton
Hematopoietic cell lineage
Osteoclast differentiation
Rap1 signaling pathway

Related Products

ITGB3 Antibodies

ITGB3 Antibodies for Homo sapiens (Human)

ITGB3 Antibodies for Human

ITGB3 Antibodies for

ITGB3 Proteins

ITGB3 Proteins for Homo sapiens (Human)

ITGB3 ELISA Kit

ITGB3 ELISA Kit for Homo sapiens (Human)

Most popular with customers

Newsletters

Get all the latest information on Events, Sales and Offers. Sign up for newsletter today.

Copyright © 2007-2018 www.cusabio.com CUSABIO TECHNOLOGY LLC All Rights Reserved.

Wait!

Join the 20,000 subscribers to get research hotpots, technical tips, latest information on events, sales and offers.

Sign up now to get your $50 coupon for protein expression service!

We don't deal in spam.