Code | CSB-AP004901HU |
Product Type | Tumor Necrosis Factor |
Size | US$65 |
Uniprot No. | P50591 |
Lead Time | 5-10 business days |
Storage Buffer | Lyophilized from a 0.2 μm Filtered 150 mM NaCl |
Alias | Tumor Necrosis Factor Ligand Superfamily Member 10; Apo-2 Ligand; Apo-2L; TNF-Related Apoptosis-Inducing Ligand; Protein TRAIL; CD253; TNFSF10; APO2L; TRAIL |
Species | Homo sapiens (Human) |
Biological_Activity | The ED50 as determined in a cytotoxicity assay using L?929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D is less than 50 ng/ml. |
Purity | Greater than 95% as determined by SDS-PAGE. |
Endotoxin | Less than 1.0 EU/μg as determined by LAL method. |
Sequence | RERGPQRVAAHITGTRGRSNTLSSPNSKNEKALGRKINSWESSRSGHSFLSNLHLRNGELVIHEKGFYYIYSQTYFRFQEEIKENTKNDKQMVQYIYKYTSYPDPILLMKSARNSCWSKDAEYGLYSIYQGGIFELKENDRIFVSVTNEHLIDMDHEASFFGAFLVG |
Research Area | Cancer |
Source | E.coli |
Gene Names | TNFSF10 |
Expression Region | 115-281aa |
Tag Info | Tag-Free |
Mol. Weight | 19.5 kDa |
Protein Description | Partial |
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Function | Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG |
Subcellular Location | Membrane, Single-pass type II membrane protein |
Protein Families | Tumor necrosis factor family |
Tissue Specificity | Widespread; most predominant in spleen, lung and prostate. |
Database Links |
HGNC: 11925 OMIM: 603598 KEGG: hsa:8743 STRING: 9606.ENSP00000241261 UniGene: Hs.478275 |
Pathway |
Apoptosis
Necroptosis Natural killer cell mediated cytotoxicity FoxO signaling pathway |
TNFSF10 Antibodies for Human
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA07475A0Rb | TNFSF10 Antibody | Human | ELISA, IHC, IF |
TNFSF10 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA07475B0Rb | TNFSF10 Antibody, HRP conjugated | Human | ELISA |
CSB-PA07475C0Rb | TNFSF10 Antibody, FITC conjugated | Human | ELISA |
CSB-PA07475D0Rb | TNFSF10 Antibody, Biotin conjugated | Human | ELISA |
CSB-PA023985GA01HU | TNFSF10 Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA272904 | TNFSF10 Antibody | Human | ELISA,WB,IF |
CSB-PA005996 | TNFSF10 Antibody | Human | WB,ELISA |
TNFSF10 Antibodies for
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA004326 | TNFSF10 Antibody | Human | WB,IHC,IF,ELISA |
TNFSF10 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP023985HU CSB-BP023985HU CSB-MP023985HU |
Recombinant Human Tumor necrosis factor ligand superfamily member 10(TNFSF10),partial | Yeast Baculovirus Mammalian cell |
CSB-EP023985HU | Recombinant Human Tumor necrosis factor ligand superfamily member 10(TNFSF10) ,partial | E.coli |
CSB-CF023985HU | Recombinant Human Tumor necrosis factor ligand superfamily member 10(TNFSF10) | in vitro E.coli expression system |
CSB-RP074754h | Recombinant Human Tumor necrosis factor ligand superfamily member 10(TNFSF10) ,partial | E.coli |
TNFSF10 ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E04750h | Human soluble tumor necrosis factor-related apoptosis inducing ligand,sTRAIL ELISA KIT | serum, plasma, cell culture supernates, urine, cerebrospinal fluid(CSF) | 7.81 pg/mL |
TNFSF10 ELISA Kit for Rattus norvegicus (Rat)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E13904r | Rat tumor necrosis factor-related apoptosis inducing ligand,TRAIL ELISA Kit | serum, plasma, tissue homogenates | 3.9 pg/mL |
Recombinant Naja kaouthia Cobra venom factor,partial
Express system: E.coli
Species: Naja kaouthia (Monocled cobra) (Naja siamensis)
Recombinant Human Ribonucleoside-diphosphate reductase large subunit(RRM1)
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Mouse Tyrosine-protein kinase Lyn(Lyn)
Express system: E.coli
Species: Mus musculus (Mouse)
Recombinant Human Proteasome subunit beta type-8(PSMB8)
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Human Calcium-dependent phospholipase A2(PLA2G5)
Express system: Yeast
Species: Homo sapiens (Human)
Recombinant Rat Neuroendocrine convertase 2(Pcsk2)
Express system: E.coli
Species: Rattus norvegicus (Rat)
Recombinant Human E3 SUMO-protein ligase RanBP2(RANBP2),partial
Express system: Yeast
Species: Homo sapiens (Human)
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