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| Code | CSB-AP004901HU |
| Product Type | Tumor Necrosis Factor |
| Size |
$65Purchase it in Cusabio online store (Shop online in the US. Customers outside the US, please order from local distributors.) |
| Uniprot No. | P50591 |
| Image |
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| Storage Buffer | Lyophilized from a 0.2 μm Filtered 150 mM NaCl |
| Alias | Tumor Necrosis Factor Ligand Superfamily Member 10; Apo-2 Ligand; Apo-2L; TNF-Related Apoptosis-Inducing Ligand; Protein TRAIL; CD253; TNFSF10; APO2L; TRAIL |
| Species | Homo sapiens (Human) |
| Biological_Activity | The ED50 as determined in a cytotoxicity assay using L?929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D is less than 50 ng/ml. |
| Purity | Greater than 95% as determined by SDS-PAGE. |
| Endotoxin | Less than 1.0 EU/μg as determined by LAL method. |
| Sequence | RERGPQRVAAHITGTRGRSNTLSSPNSKNEKALGRKINSWESSRSGHSFLSNLHLRNGELVIHEKGFYYIYSQTYFRFQEEIKENTKNDKQMVQYIYKYTSYPDPILLMKSARNSCWSKDAEYGLYSIYQGGIFELKENDRIFVSVTNEHLIDMDHEASFFGAFLVG |
| Research Area | Cancer |
| Source | E.coli |
| Gene Names | TNFSF10 |
| Expression Region | 115-281aa |
| Tag Info | Tag-Free |
| Mol. Weight | 19.5 kDa |
| Protein Description | Partial |
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| Function | Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG |
| Subcellular Location | Membrane, Single-pass type II membrane protein |
| Protein Families | Tumor necrosis factor family |
| Tissue Specificity | Widespread; most predominant in spleen, lung and prostate. |
| Database Links |
HGNC: 11925 OMIM: 603598 KEGG: hsa:8743 STRING: 9606.ENSP00000241261 UniGene: Hs.478275 |
| Pathway |
Apoptosis
Necroptosis Natural killer cell mediated cytotoxicity FoxO signaling pathway |
TNFSF10 Antibodies for Human
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA07475A0Rb | TNFSF10 Antibody | Human | ELISA, IHC, IF |
TNFSF10 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA07475B0Rb | TNFSF10 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA07475C0Rb | TNFSF10 Antibody, FITC conjugated | Human | ELISA |
| CSB-PA07475D0Rb | TNFSF10 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA023985GA01HU | TNFSF10 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA272904 | TNFSF10 Antibody | Human | ELISA,WB,IF |
| CSB-PA005996 | TNFSF10 Antibody | Human | WB,ELISA |
TNFSF10 Antibodies for
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA004326 | TNFSF10 Antibody | Human | WB,IHC,IF,ELISA |
TNFSF10 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP023985HU CSB-BP023985HU CSB-MP023985HU |
Recombinant Human Tumor necrosis factor ligand superfamily member 10(TNFSF10),partial | Yeast Baculovirus Mammalian cell |
| CSB-EP023985HU | Recombinant Human Tumor necrosis factor ligand superfamily member 10(TNFSF10) ,partial | E.coli |
| CSB-CF023985HU | Recombinant Human Tumor necrosis factor ligand superfamily member 10(TNFSF10) | in vitro E.coli expression system |
| CSB-EP023985HUe0 | Recombinant Human Tumor necrosis factor ligand superfamily member 10(TNFSF10) ,partial | E.coli |
TNFSF10 ELISA Kit for Homo sapiens (Human)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-E04750h | Human soluble tumor necrosis factor-related apoptosis inducing ligand,sTRAIL ELISA KIT | serum, plasma, cell culture supernates, urine, cerebrospinal fluid(CSF) | 7.81 pg/mL |
TNFSF10 ELISA Kit for Rattus norvegicus (Rat)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-E13904r | Rat tumor necrosis factor-related apoptosis inducing ligand,TRAIL ELISA Kit | serum, plasma, tissue homogenates | 3.9 pg/mL |
Recombinant Mouse Interleukin-7 receptor subunit alpha(Il7r),partial
Express system: Yeast
Species: Mus musculus (Mouse)
Recombinant Human Cytochrome c-type heme lyase(HCCS)
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Mouse Prostate stem cell antigen(Psca)
Express system: Yeast
Species: Mus musculus (Mouse)
Recombinant Human Ras-related protein Rab-10(RAB10),partial
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Human Coagulation factor XI(F11),partial
Express system: E.coli
Species: Homo sapiens (Human)
