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Tumor necrosis factor ligand superfamily member 10 is a protein in humans that is encoded by TNFSF10 gene.TRAIL is a cytokine that is produced and secreted by most normal tissue cells. It causes apoptosis primarily in tumor cells, by binding to certain death receptors. TRAIL and its receptors have been used as the targets of several anti-cancer therapeutics since the mid-1990s, such as Mapatumumab. However, as of 2013, these have not shown significant survival benefit. TRAIL has also been designated CD253 (cluster of differentiation 253) and TNFSF10 (tumor necrosis factor (ligand) superfamily, member 10).
The following TNFSF10 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
TNFSF10 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA07475A0Rb | TNFSF10 Antibody |
Human | ELISA, IHC, IF |
| CSB-PA023985GA01HU | TNFSF10 Antibody |
Human,Mouse,Rat | ELISA,WB |
| CSB-PA272904 | TNFSF10 Antibody |
Human | ELISA,WB,IF |
| CSB-PA004326 | TNFSF10 Antibody |
Human | WB, IHC, IF, ELISA |
| CSB-PA005996 | TNFSF10 Antibody |
Human | WB, ELISA |
TNFSF10 Proteins for Mus musculus (Mouse)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP023985MO CSB-EP023985MO CSB-BP023985MO CSB-MP023985MO CSB-EP023985MO-B |
Recombinant Mouse Tumor necrosis factor ligand superfamily member 10 (Tnfsf10) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TNFSF10 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP023985HU CSB-BP023985HU CSB-MP023985HU CSB-EP023985HU-B |
Recombinant Human Tumor necrosis factor ligand superfamily member 10 (TNFSF10), partial |
Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP023985HU | Recombinant Human Tumor necrosis factor ligand superfamily member 10 (TNFSF10), partial |
E.coli |
| CSB-CF023985HU | Recombinant Human Tumor necrosis factor ligand superfamily member 10 (TNFSF10) |
in vitro E.coli expression system |
| CSB-AP004901HU | Recombinant Human Tumor necrosis factor ligand superfamily member 10 (TNFSF10), partial (Active) |
E.coli |
| CSB-EP023985HUe0 | Recombinant Human Tumor necrosis factor ligand superfamily member 10 (TNFSF10), partial |
E.coli |
TNFSF10 ELISA Kit for Homo sapiens (Human)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-E04750h | Human soluble tumor necrosis factor-related apoptosis inducing ligand,sTRAIL ELISA KIT |
serum, plasma, tissue homogenates | 3.9 pg/ml |
TNFSF10 ELISA Kit for Mus musculus (Mouse)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-E07371m | Mouse soluble tumor necrosis factor-related apoptosis inducing ligand,sTRAIL ELISA KIT |
serum, plasma, tissue homogenates | 7.8 pg/ml |
TNFSF10 ELISA Kit for Rattus norvegicus (Rat)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-E13904r | Rat tumor necrosis factor-related apoptosis inducing ligand,TRAIL ELISA Kit |
serum, plasma, tissue homogenates | 3.9 pg/mL |
Tumor necrosis factor ligand superfamily member 10 is a protein in humans that is encoded by TNFSF10 gene. TRAIL is a cytokine that is produced and secreted by most normal tissue cells. It causes apoptosis primarily in tumor cells, by binding to certain death receptors. TRAIL and its receptors have been used as the targets of several anti-cancer therapeutics since the mid-1990s, such as Mapatumumab. However, as of 2013, these have not shown significant survival benefits. TRAIL has also been designated CD253 (cluster of differentiation 253) and TNFSF10 (tumor necrosis factor (ligand) superfamily, member 10).
