TNFSF10 Research Reagents

Tumor necrosis factor ligand superfamily member 10 is a protein in humans that is encoded by TNFSF10 gene.TRAIL is a cytokine that is produced and secreted by most normal tissue cells. It causes apoptosis primarily in tumor cells, by binding to certain death receptors. TRAIL and its receptors have been used as the targets of several anti-cancer therapeutics since the mid-1990s, such as Mapatumumab. However, as of 2013, these have not shown significant survival benefit. TRAIL has also been designated CD253 (cluster of differentiation 253) and TNFSF10 (tumor necrosis factor (ligand) superfamily, member 10).

The following TNFSF10 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

TNFSF10 Antibodies

TNFSF10 Antibodies for Homo sapiens (Human)

TNFSF10 Proteins

TNFSF10 Proteins for Mus musculus (Mouse)

TNFSF10 Proteins for Homo sapiens (Human)

TNFSF10 ELISA Kit

TNFSF10 ELISA Kit for Homo sapiens (Human)

TNFSF10 ELISA Kit for Mus musculus (Mouse)

TNFSF10 ELISA Kit for Rattus norvegicus (Rat)

TNFSF10 Background

Tumor necrosis factor ligand superfamily member 10 is a protein in humans that is encoded by TNFSF10 gene. TRAIL is a cytokine that is produced and secreted by most normal tissue cells. It causes apoptosis primarily in tumor cells, by binding to certain death receptors. TRAIL and its receptors have been used as the targets of several anti-cancer therapeutics since the mid-1990s, such as Mapatumumab. However, as of 2013, these have not shown significant survival benefits. TRAIL has also been designated CD253 (cluster of differentiation 253) and TNFSF10 (tumor necrosis factor (ligand) superfamily, member 10).

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