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| Code | CSB-AP002351HU |
| Product Type | Tumor Necrosis Factor |
| Size |
US$112Purchase it in Cusabio online store (Shop online in the US. Customers outside the US, please order from local distributors.) |
| Uniprot No. | Q9UNG2 |
| Lead Time | 5-10 business days |
| Image | |
| Storage Buffer | 0.2 m filtered PBS, pH 7.4 ,lyophilized |
| Alias | Activation-inducible TNF-related ligand, Glucocorticoid-induced TNF-related ligand, hGITRL |
| Species | Homo sapiens (Human) |
| Biological_Activity | Fully biologically active when compared to standard. The biological activity as determined by stimulation of IL-8 production using human PBMC is in a concentration range of 0.1-10 ng/ml. |
| Purity | >98% as determined by SDS-PAGE and HPLC. |
| Endotoxin | Less than 1.0 EU/μg as determined by LAL method. |
| Sequence | ETAKEPCMAK FGPLPSKWQM ASSEPPCVNK VSDWKLEILQ NGLYLIYGQV APNANYNDVA PFEVRLYKNK DMIQTLTNKS KIQNVGGTYE LHVGDTIDLI FNSEHQVLKN NTYWGIILLA NPQFIS |
| Research Area | Cancer |
| Source | E.coli |
| Gene Names | TNFSF18 |
| Expression Region | 74-199aa |
| Tag Info | Tag-Free |
| Mol. Weight | 14.3 kDa |
| Protein Description | Partial |
| PubMed ID | 16710414; 15489334; 14702039; 12975309; 10074428; 10037686; 17449724; 23892569; 18040044 |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
| Function | Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B. Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1 |
| Subcellular Location | Cell membrane, Single-pass type II membrane protein |
| Protein Families | Tumor necrosis factor family |
| Tissue Specificity | Expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. |
| Database Links |
HGNC: 11932 OMIM: 603898 KEGG: hsa:8995 STRING: 9606.ENSP00000385470 UniGene: Hs.248197 |
TNFSF18 Antibodies for Human
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA891791ESR1HU | TNFSF18 Antibody | Human | ELISA, IHC |
TNFSF18 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP891791HU CSB-EP891791HU CSB-BP891791HU CSB-MP891791HU |
Recombinant Human Tumor necrosis factor ligand superfamily member 18(TNFSF18),partial | Yeast E.coli Baculovirus Mammalian cell |
TNFSF18 ELISA Kit for Homo sapiens (Human)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-EL023993HU | Human Tumor necrosis factor ligand superfamily member 18(TNFSF18) ELISA kit | Request Information |
Recombinant Human Putative inactive neutral ceramidase B(ASAH2B)
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Rat Sulfotransferase 1A1(Sult1a1)
Express system: E.coli
Species: Rattus norvegicus (Rat)
Recombinant Mouse Plasminogen activator inhibitor 1(Serpine1)
Express system: Yeast
Species: Mus musculus (Mouse)
Recombinant Human Junctional adhesion molecule B(JAM2),partial
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Rat Alpha-2-macroglobulin(A2m),partial
Express system: Yeast
Species: Rattus norvegicus (Rat)
