RALY Antibody

Datasheet

Code	CSB-PA249029
Size	US$297
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Image	Western blot analysis of extracts from Jurkat cells and COLO205 cells, using RALY antibody.
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) RALY Polyclonal antibody

Uniprot No.

Q9UKM9

Target Names

RALY

Alternative Names

Autoantigen p542 antibody; Heterogeneous nuclear ribonucleoprotein C-like 2 antibody; hnRNP associated with lethal yellow protein homolog antibody; hnRNP core protein C-like 2 antibody; MGC117312 antibody; P542 antibody; RALY antibody; RALY_HUMAN antibody; RNA binding protein (autoantigenic hnRNP associated with lethal yellow) antibody; RNA binding protein (autoantigenic) antibody; RNA binding protein autoantigenic (hnRNP associated with lethal yellow homolog (mouse)) antibody; RNA-binding protein Raly antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Synthesized peptide derived from internal of Human RALY.

Immunogen Species

Homo sapiens (Human)

Clonality

Polyclonal

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Tested Applications

ELISA,WB

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:3000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

RNA-binding protein that acts as a transcriptional cofactor for cholesterol biosynthetic genes in the liver. Binds the lipid-responsive non-coding RNA LeXis and is required for LeXis-mediated effect on cholesterogenesis. May be a heterogeneous nuclear ribonucleoprotein (hnRNP).

Gene References into Functions

hnRNP RALY regulates PMID: 28972179
RALY promotes Protein Arginine Methyltransferase 1 alternatively spliced isoform v2 relative expression and metastatic potential in breast cancer cells PMID: 28733251
RALY is a poly-U binding protein and as a regulator of H1FX and ANXA1 in mammalian cells. PMID: 28379492
People with lower level of RALYL expression had a poorer survival rate. PMID: 22994768

Subcellular Location

Nucleus.

Protein Families

RRM HNRPC family, RALY subfamily

Tissue Specificity

Expressed in heart, brain, lung, liver, skeletal muscle, kidney and pancreas. Weakly expressed in placenta.

Database Links

HGNC: 15921

OMIM: 614663

KEGG: hsa:22913

STRING: 9606.ENSP00000246194

UniGene: Hs.136947

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Service

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Protein Service

Gene Synthesis Service

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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