Human Tumor necrosis factor receptor superfamily member 9(TNFRSF9) ELISA kit

Code CSB-EL023984HU
See More Details 24T ELISA kits trial application
Product Type ELISA Kit
Size 96T,5×96T,10×96T
Uniprot No. Q07011
Lead Time 7-14 working days
Abbreviation TNFRSF9
Target Name tumor necrosis factor receptor superfamily, member 9
Alias 4-1BB, CD137, CDw137, ILA, MGC2172, 4-1BB ligand receptor|CD137 antigen|T cell antigen ILA|homolog of mouse 4-1BB|induced by lymphocyte activation (ILA)|interleukin-activated receptor, homolog of mo
Species Homo sapiens (Human)
Sample Types serum, plasma, tissue homogenates
Detection Range 7.8 pg/mL-500 pg/mL
Sensitivity 1.95 pg/mL
Assay Time 1-5h
Sample Volume 50-100ul
Detection Wavelength 450 nm
Research Area Others
Protocol
Protocol may be improved. Please feel free to contact CUSABIO product specialist to obtain the latest version.
Assay Principle quantitative
Measurement Sandwich
Target Details This protein is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.
HGNC 11924
RGD 1598208
MGI 1101059
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Function Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation.
Subcellular Location Membrane, Single-pass type I membrane protein
Tissue Specificity Expressed on the surface of activated T-cells.
Database Links

HGNC: 11924

OMIM: 602250

KEGG: hsa:3604

STRING: 9606.ENSP00000366729

UniGene: Hs.738942

Pathway Target Therapy

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