Recombinant Human Interleukin-4 protein(IL4) (Active)

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Code CSB-AP001711HU
Product Type Interleukin
Size US$112Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. P05112
Lead Time 5-10 business days
Storage Buffer 0.2 μm filtered PBS, pH 7.4 ,lyophilized
Alias IL-4, BSF-1, Binetrakin, Lymphocyte stimulatory factor 1, Pitrakinra
Species Homo sapiens (Human)
Biological_Activity Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 0.2 ng/ml, corresponding to a specific activity of >5.0x106 IU/mg.
Purity >98% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Research Area Immunology
Source E.coli
Gene Names IL4
Expression Region 25-153aa
Tag Info Tag-Free
Mol. Weight 15.0 kDa
Protein Description Full Length of Mature Protein
PubMed ID 3016727; 2535858; 7806280; 15489334; 3257560; 1993171; 1400355; 1511746; 10219247; 1932028; 1569578; 1567880; 1567881; 1609277; 1946344; 8151703; 7664036; 14681304
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Function Participates in at least several B-cell activation processes as well as of other cell types
Involvement in disease Ischemic stroke (ISCHSTR)
Subcellular Location Secreted
Protein Families IL-4/IL-13 family
Database Links

HGNC: 6014

OMIM: 147780

KEGG: hsa:3565

STRING: 9606.ENSP00000231449

UniGene: Hs.73917

Pathway Jak-STAT signaling pathway
PI3K-Akt signaling pathway
Fc epsilon RI signaling pathway
Hematopoietic cell lineage
IL-17 signaling pathway
T cell receptor signaling pathway
Th1 and Th2 cell differentiation
Th17 cell differentiation

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