Recombinant Human Interleukin-4 protein(IL4) (Active)

Code CSB-AP001711HU
Product Type Interleukin
Size Pls inquiry other sizesPurchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. P05112
Image
Storage Buffer 0.2 μm filtered PBS, pH 7.4 ,lyophilized
Alias IL-4, BSF-1, Binetrakin, Lymphocyte stimulatory factor 1, Pitrakinra
Species Homo sapiens (Human)
Biological_Activity Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 0.2 ng/ml, corresponding to a specific activity of >5.0x106 IU/mg.
Purity >98% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence HKCDITLQEI IKTLNSLTEQ KTLCTELTVT DIFAASKNTT EKETFCRAAT VLRQFYSHHE KDTRCLGATA QQFHRHKQLI RFLKRLDRNL WGLAGLNSCP VKEANQSTLE NFLERLKTIM REKYSKCSS
Research Area Immunology
Source E.coli
Gene Names IL4
Expression Region 25-153aa
Product Info Tag-Free
Mol. Weight 15.0 kDa
Protein Description Full Length of Mature Protein
PubMed ID 3016727; 2535858; 7806280; 15489334; 3257560; 1993171; 1400355; 1511746; 10219247; 1932028; 1569578; 1567880; 1567881; 1609277; 1946344; 8151703; 7664036; 14681304
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Function Participates in at least several B-cell activation processes as well as of other cell types
Involvement in disease Ischemic stroke (ISCHSTR)
Subcellular Location Secreted
Protein Families IL-4/IL-13 family
Database Links

HGNC: 6014

OMIM: 147780

KEGG: hsa:3565

STRING: 9606.ENSP00000231449

UniGene: Hs.73917

Pathway Jak-STAT signaling pathway
PI3K-Akt signaling pathway
Fc epsilon RI signaling pathway
Hematopoietic cell lineage
IL-17 signaling pathway
T cell receptor signaling pathway
Th1 and Th2 cell differentiation
Th17 cell differentiation

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