Recombinant Mouse Interleukin-2 protein(Il2) (Active)

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Code CSB-AP003281MO
Product Type Interleukin
Size US$112Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. P04351
Lead Time 5-10 business days
Storage Buffer 0.2 μm filtered PBS, pH 7.4 ,lyophilized
Alias IL-2, TCGF
Species Mus musculus (Mouse)
Biological_Activity Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine CTLL-2 cells is less than 0.2 ng/ml, corresponding to a specific activity of >5.0x106 IU/mg.
Purity >95% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Research Area Immunology
Source E.coli
Gene Names Il2
Expression Region 21-169aa
Tag Info Tag-Free
Mol. Weight 17.2 kDa
Protein Description Full Length of Mature Protein
PubMed ID 6240025; 2578624; 3918306; 3003564; 10779485; 19468303; 1420317; 8319981; 8262055
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Function Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.
Subcellular Location Secreted
Protein Families IL-2 family
Database Links

KEGG: mmu:16183

STRING: 10090.ENSMUSP00000029275

UniGene: Mm.14190

Pathway Jak-STAT signaling pathway
PI3K-Akt signaling pathway
T cell receptor signaling pathway
Th1 and Th2 cell differentiation
Th17 cell differentiation

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