Recombinant Mouse Interleukin-4 protein(Il4) (Active)

In Stock
Code CSB-AP003301MO
Product Type Interleukin
Size US$112Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. P07750
Lead Time 5-10 business days
Image
Storage Buffer 0.2 μm filtered , PBS, pH 7.4 ,lyophilized
Alias IL-4, B-cell growth factor 1, B-cell stimulatory factor 1, BSF-1, IGG1 induction factor
Species Mus musculus (Mouse)
Biological_Activity Fully biologically active when compared to standard. The ED50 as determined by the dose-dependant prolifiration of Murine HT-2 cells is less then 2 ng/ml, corresponding to a Specific Activity of >5x105 IU/mg.
Purity >97% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence M+HIHGCDKNH LREIIGILNE VTGEGTPCTE MDVPNVLTAT KNTTESELVC RASKVLRIFY LKHGKTPCLK KNSSVLMELQ RLFRAFRCLD SSISCTMNES KSTSLKDFLE SLKSIMQMDY S
Research Area Immunology
Source E.coli
Gene Names Il4
Expression Region 21-140aa
Tag Info Tag-Free
Mol. Weight 13.5 kDa
Protein Description Full Length of Mature Protein
PubMed ID 3005865; 3029676; 3083412; 3498301; 15489334; 1993171
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Function Participates in at least several B-cell activation processes as well as of other cell types
Subcellular Location Secreted
Protein Families IL-4/IL-13 family
Database Links

KEGG: mmu:16189

STRING: 10090.ENSMUSP00000000889

UniGene: Mm.276360

Pathway Jak-STAT signaling pathway
PI3K-Akt signaling pathway
Fc epsilon RI signaling pathway
Hematopoietic cell lineage
IL-17 signaling pathway
T cell receptor signaling pathway
Th1 and Th2 cell differentiation
Th17 cell differentiation

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